The signs and symptoms of Sjögren's might differ from person to person and resemble those of other conditions, making a diagnosis difficult. The following tests can be used to confirm Sjögren's and rule out other conditions:

• Blood Tests: Evaluates the presence of specific antibodies that are common in Sjögren's.

• Eye Tests: The Schirmer test is a common test that measures eye dryness and tear production. The ocular surface staining test checks for damage and dryness on the surfaces of eyes.

• Imaging: Sialogram and salivary scintigraphy are tests that check the function of salivary glands and how much saliva is produced.

• Lip Biopsy: Detects the presence of inflammation and inflammatory cells in the salivary glands.

Treatment for Sjögren's is dependent on the affected body parts, but most commonly targets dry eye and dry mouth.

Medications

Medications used for managing Sjögren's include:

• Artificial Tears and Prescription Eye Drops: Alleviates dryness and inflammation in the eyes.
  

• Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Manages pain related to arthritis and reduces inflammation.
  

• Disease-Modifying Anti-Rheumatic Drugs (DMARDs): Hydroxychloroquine and methotrexate are types of DMARDs that target systemic symptoms.
  

• Saliva Stimulants: Enhances saliva production to improve dry mouth.