Multiple Sclerosis (MS)

Multiple sclerosis (MS) is a chronic disease of the central nervous system (brain and spinal cord) that occurs when the immune system attacks the layer surrounding nerve cells, known as the myelin sheath. When myelin is lost, it damages nerves and disrupts communication between the brain and the rest of the body.

Fatigue

Muscle weakness, spasms, and stiffness

Tingling and numbness in the limbs

Bladder problems

Difficulty balancing, walking, and standing

Tightness or squeezing sensation around the torso or chest (MS hug)

For individuals showing signs and symptoms that are consistent with multiple sclerosis, doctors may conduct the following tests to confirm a diagnosis:

  • Blood Tests: Used to eliminate other conditions that have similar symptoms to MS and to identify indicators that are associated with MS.
  • Spinal Tap (Lumbar Puncture): A needle is inserted into the spine to remove a portion of spinal fluid, which is then tested for infections or abnormalities in antibodies and immune cells.
  • Magnetic Resonance Imaging (MRI): Detects lesions in the brain or spinal cord. Lesions are caused by damage to the myelin sheath surrounding the nerves.
  • Neurological Examination: Checks for any abnormalities or weakness in vision, limb strength, speech, balance, coordination, walking, and reflexes.
  • Evoked Potential Test: This test requires patients to watch visual patterns while electrodes are applied to measure the time it takes for information to travel down the nerve pathways.

Although there is no known cure for MS, treatments and medications can effectively reduce its signs and symptoms.

Treatment for Signs and Symptoms

Below are a few examples of treatment options for reducing some signs and symptoms of MS:

  • Therapy: Physical therapy and occupational therapy can assist individuals with MS in building muscle strength and learning techniques to perform everyday tasks on their own.
  • Muscle Relaxants and Sedatives: Muscle relaxants and sedatives can assist individuals with MS in alleviating muscle pain, stiffness, and spasticity that may occur.
  • Treatment for Bladder Problems: Bladder issues may lead to bladder infections, hygiene problems, and kidney damage. Treatment for bladder issues could include diet changes or medications to help with bladder control.
  • Medications to Reduce Fatigue: There are some medications that can help manage chronic fatigue for people with MS.
Treatment to Modify Progression
  • Disease modifying therapies (DMTs) may be administered as oral medications, injections, or infusions. These are medications that are used to reduce the number and severity of MS relapses and to delay progression of the disease.
Treatment for MS Relapses
  • A relapse is a flare-up of symptoms. If a patient is experiencing a current relapse, steroids like methylprednisolone (intravenous injections) or prednisone (pills) are used. Steroids can alleviate symptoms of a flare-up; however, they do not alter the course of the disease.

Ongoing Research

Multiple sclerosis is a disease that requires more effective treatment options. To find these new treatments for MS, further research is necessary.

Current Research Studies

There are over 480 multiple sclerosis research studies that are actively recruiting participants. Visit Clinicaltrials.gov to find MS research studies near you.

Featured Study

Resources

Find an online community of fellow patients, caregivers, and advocates below
as well as some other general resources!

National Multiple Sclerosis Society
The National Multiple Sclerosis Society is an organization whose mission is to help find a cure for MS and empower people living with MS.
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Multiple Sclerosis Foundation
A support group created by the Multiple Sclerosis Foundation that welcomes those who are affected by MS.
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Reddit Group: r/MultipleSclerosis
A Reddit community group for people with MS and their family and friends, focusing on conversations about support, research, drug therapies, and more.
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Multiple Sclerosis Support Group
A support group to share stories, ask questions, and connect with other people living with MS.
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National Multiple Sclerosis Society
The National Multiple Sclerosis Society is an organization whose mission is to help find a cure for MS and empower people living with MS.
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MS International Federation
The MS International Federation is a global network of MS organizations, people affected by MS, volunteers, and staff who are working to improve the quality of life for those affected by MS.
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Multiple Sclerosis Association of America (MSAA)
The Multiple Sclerosis Association of America (MSAA) is a non-profit organization dedicated to enhancing the lives of people with MS, their families, and care partners by providing support and services.
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Multiple Sclerosis Foundation
The Multiple Sclerosis Foundation provides programs and support services to those affected by MS and promotes public awareness.
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The MSing Link
This podcast hosted by Dr. Gretchen Hawley discusses different symptom management strategies for those with MS. MS specialists are also brought in to discuss new developments in the field.
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RealTalk MS
The National MS Society has teamed up with the RealTalk MS podcast where the host, Jon Strum, discusses the latest updates in MS news, research, advocacy and support for people affected by MS.
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MS and Your Mental Health
Visit the website below to find different articles and resources focusing on coping with mental health for those living with multiple sclerosis.
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Emotional Well-Being and Multiple Sclerosis
The National Multiple Sclerosis Society created this website page to give people with MS who are struggling with their mental health some coping tips and resources for support.
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New Way Inflammation Impacts Cell Communication
Read the article below to learn more about how researchers have made significant progress in understanding how cells communicate during inflammation.
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New Research Suggests Inflammation Outside the Brain Contributes to MS Progression
Read the article to learn how research funded by the MS Society has found that inflammation outside the brain may contribute to the progression of MS.
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